شبكة إشعاعية ضد الأورام الكبيرة سريع

الملخص الأصلي

كما كتبه المؤلفون، بالإنجليزية arXiv:2604.03967

Spatially Fractionated Radiation Therapy (SFRT) or GRID therapy has been in existence for more than a century. GRID therapy was invented as an approach to address the challenges posed by bulky tumors. To treat patients with GRID therapy, the protocol needs to be implemented within the Treatment Planning System (TPS) software. Also, the dose needed for treatment must be validated. A few TPS software vendors such as Elekta and Varian have protocols for treating patients with GRID therapy. However, we are the first to implement the protocols within RayStation TPS. To achieve these, we used the .decimal GRID block applicator to create conformal treatment plans. For the beam modeling, several dosimetry data, and measurements such as percentage depth dose (PDD), beam profile, output, and GRID factors, were obtained for different field sizes and energies. The dose distribution from the GRID openings covered the Planning Target Volume (PTV), with the QA plan having a 98% agreement with the planned dose. Also, we used the Mapcheck2 results to verify the adjustments made to the script variables such as aperture size (hole and spacing). We developed a robust way to validate the dose needed for patient treatment using the GRID block applicator. Also, we have proposed a novel approach to standardize the clinical implementation of the GRID block in RayStation TPS.