R Miller

In an old house, beams don't break all at once. First, voids appear inside them, like in a sponge, and only later does one of the beams give way. Bones age just as quietly: the spongy part, resembling a weave of thin struts, loses its supports long before a person feels pain. Scientists decided to test whether substances that slow aging can halt this quiet dismantling of load-bearing structures.

Five different roads lead to a single destination: a long life. Some mice received drugs, others ate 40% less than usual. After eight months, seven tissues were collected from all of them: brain, liver, muscle, kidney, fat, blood. Each tissue is a separate witness, seeing what happens from its own angle.