A Neural Report Card: How Organoids Grade Brain Drugs
In a school report card, each grade speaks for itself, but you can only tell how a student is doing overall by looking at the full report. For drugs that act on the brain, such a report card was missing for a long time. Every test on a miniature brain grown in a dish gave its own signal: some genes switched on, others switched off, electrical impulses sometimes sped up and sometimes went quiet.