A needle of water: how 10,000 agents made the Navier–Stokes equations blow up
In 1934 Jean Leray proved that the Navier–Stokes equations always have solutions "in a generalized sense". Whether a solution stays smooth or can break down into a singularity he could not tell, and nobody could for ninety years. In 2000 the Clay Institute made the question one of its seven Millennium Prize problems.