Boris Rubinsky

The usual way to freeze a living cell is like trying to put a spacesuit on it: you first need to get a protective substance inside, but while it's crossing the membrane, the cell can burst from salt imbalances or get poisoned by the chemicals.

In winter, puddles freeze, and ice cracks the asphalt. Inside a living cell, freezing does something similar: ice crystals tear its membrane. To prevent this, the cell is soaked in a special solution, like antifreeze for a car. But precision is key: too little solution and ice still forms; too much and the solution itself poisons the cell.