object

capillary

A tiny blood vessel that connects arteries and veins, allowing exchange of substances.
14 related articles

Description

A capillary is the smallest type of blood vessel in the circulatory system, connecting arterioles to venules. Its thin walls, composed of a single layer of endothelial cells, allow for the efficient exchange of oxygen, carbon dioxide, nutrients, and waste products between blood and surrounding tissues. Capillaries are so narrow that red blood cells must often pass through in single file, maximizing contact with the vessel wall.

History

The existence of capillaries was first proposed by William Harvey in the 17th century, but they were observed directly by Marcello Malpighi in 1661 using a microscope.

How it works

The exchange occurs primarily through diffusion driven by concentration gradients, as well as through bulk flow due to hydrostatic and osmotic pressure differences across the capillary wall. Small molecules like oxygen and carbon dioxide diffuse directly through the endothelial cells, while larger molecules may pass through gaps between cells or via vesicles. The balance of pressures, described by the Starling equation, determines whether fluid moves into or out of the capillary.

In practice

Capillaries are central to drug delivery research, as understanding their permeability helps design nanoparticles that can cross the blood-brain barrier or target tumors.

Fun fact

The total length of capillaries in an adult human body is estimated to be about 60,000 miles, enough to circle the Earth more than twice.

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Related articles · 14

Wood remembers when it was liquid
A slice of eucalyptus a tenth of a millimeter thick is placed under a polarized light microscope, and the wood suddenly blooms: blue, yellow, and pink bands twist into spirals, forming rings and swirls. This is not paint but the play of light: the cellulose fibers that make up cell walls transmit light differently depending on their orientation.
Life from Bubbles: How Prototype Cells Gained Evolution
Life begins with a bubble. In a warm puddle on ancient Earth, fat molecules could gather into tiny spheres — prototypes of cells. Inside such a sphere, a polymer happened to be present that accelerated the uptake of new fats from the surrounding water. The bubble grew, divided, and passed its composition to offspring.
Biological Physics2026-08-081 minarXiv:2608.08096express
The Ear as a Living Amplifier
Sound enters the ear and hits a thin membrane inside the cochlea, the spiral organ in the inner ear. This membrane doesn't just vibrate like a string; it actively pushes the vibrations when they are weak and stops when they are strong. That's how the ear hears both a whisper and a loud conversation. Scientists built a model where each piece of the membrane is a tiny pendulum with a spring.
q-bio.TO2026-07-212 minarXiv:2607.19269express
How Lung Capillaries Dampen the Pulse Wave
A subway train races through a tunnel, yet passengers in the last car barely sway. Blood flow in the lungs works much the same way: the heart pumps blood in powerful spurts, but by the time it reaches the veins, the pulsation has almost vanished.
Fluid Dynamics2026-05-202 minarXiv:2605.21567express
Cilia Pumps: The Speed-Pressure Trade-off
Millions of cilia, thin hairs, work inside the tiny ducts of our bodies. They beat in synchrony, like the oars of a galley, pushing viscous mucus or fluid along. The authors of a new study propose viewing the ciliary carpet as an active porous medium — something like a sponge that squeezes and releases itself, driving water through.
Mesoscale2026-04-091 minarXiv:2604.07946express
Water in Nanopores: Layer by Layer or All at Once
In a narrow gap between two plates, water from humid air collects on its own: this is capillary condensation. If the gap is only a few nanometers wide, water no longer behaves like a continuous liquid: every molecule counts.
One-Way Flow: The Secret of the Lymphatic Pump
Lymphatic vessels are one-way streets. Through them, fluid flows only forward thanks to tiny flap valves. These valves open in just one direction, creating asymmetry, directionality, without which the flow would stop. In the lab, scientists modeled a vessel and sent compression waves along it, like a parade of gentle nudges.
How droplets inside cells shape membranes
Inside a living cell, droplets float that don't mix with the surrounding fluid, like oil in water. These droplets aren't just passive clumps; they actively press on membranes and make them bend. Scientists observed this process in living plant cells, reproduced it in a test tube, and simulated it on a computer.
Fluid Dynamics2026-03-152 minarXiv:2603.14195express
Chameleon Fluid: When Ripples Go Against the Flow
In ordinary water, ripples from a thrown stone spread in even concentric circles. But imagine a liquid whose molecules are like tiny screws with a right-handed thread. In such a medium, the surface acts like a one-way street: waves can only travel in a certain direction.
Biological Physics2026-03-111 minarXiv:2603.11020express
Cilia Surfers: How Microwaves Carry Particles
Cilia are tiny hairs on cell surfaces. They beat like oars, moving fluid. In the lungs, they push dust and microbes out. But their lengths vary: in humans, they are thousandths of a millimeter; in comb jellies, several millimeters. How do such different cilia work together? Scientists built a machine that jerks fluid sharply, as if a cilium had struck. They filmed it with a high-speed camera.
Fluid Dynamics2026-02-281 minarXiv:2603.00475express
A Drop on the Doorstep
Water in a narrow gap crawls on its own: that's the capillary effect that pulls sap up a stem. But if it hits a step, the liquid can freeze, like a traveler before a high threshold. Scientists built tiny glass channels and watched when a drop steps over the ledge and when it gets stuck.
Fluid Dynamics2026-02-201 minarXiv:2602.18349express
Bubbles Line Up on Their Own
In a narrow vertical tube, alcohol flows upward, surrounded by water, and carbon dioxide bubbles are born inside it. As soon as they appear, they rush toward the axis of the flow, as if an invisible hand gathers them into a neat chain.
Medical Physics2026-02-101 minarXiv:2602.10011express
Why Blood Pressure Won't Drop: Loops in the Vessels
Water in a circular hose, pumped around by a pump, won't stop even if you pinch one section: the flow finds a detour and keeps going around. That's roughly how some parts of our circulatory system are arranged — not as single pipes but as closed loops. Scientists built a computer model of blood flow and compared two scenarios: an open vessel and a closed loop.
Drops That Hang by a Hair
A drop of water squeezed between two close surfaces turns into a tiny bridge. Such bridges are everywhere: they hold sand grains together in wet sand, make hair clump after a shower, and even help insects walk up walls. Scientists took three kinds of surfaces: plain glass, glass with a water-repellent coating, and glass infused with silicone oil.