A nanoscale particle of gold, often studied for its unique properties.Gold nanoparticles are particles of gold with dimensions between 1 and 100 nanometers. At this scale, gold exhibits properties dramatically different from bulk gold: it appears red or purple in solution, has a very high surface-to-volume ratio, and can strongly absorb and scatter light due to localized surface plasmon resonance. These properties make gold nanoparticles valuable in sensing, imaging, and medical therapy.
Gold nanoparticles have been used since ancient times for staining glass, but the scientific understanding began with Michael Faraday's 1857 experiments on colloidal gold. Modern controlled synthesis and applications developed in the late 20th century.
The unique optical behavior arises from conduction electrons on the nanoparticle's surface oscillating collectively when excited by light. This resonance depends on the particle's size, shape, and surrounding medium, so changes in the environment (like binding of a molecule) shift the color. Additionally, the high surface area allows functionalization with antibodies or drugs, and the particles can convert absorbed light into heat, enabling targeted thermal therapy.
They are used in rapid diagnostic tests (e.g., pregnancy tests), cancer photothermal therapy, drug delivery, and as contrast agents in electron microscopy.
A single gold nanoparticle can be as small as 1/1000th the width of a human hair, yet it can absorb light so efficiently that it can be used to kill cancer cells with heat.







