
The interstellar medium is the matter and radiation that exists in the space between star systems in a galaxy.The interstellar medium (ISM) is the ensemble of gas (99% of mass, mostly hydrogen and helium), dust (1%, particles of silicates, carbon, ices), cosmic rays, magnetic fields, and radiation between stars. It exists in different phases: cold molecular clouds with temperatures around 10 kelvins (where stars form), warm neutral medium (~10,000 K), hot ionized gas (~1 million K), inflated by supernova explosions. The average density is about 1 atom per cm³, but in clumps it can be millions of times higher. The ISM absorbs, scatters, and re-emits light, so when observing distant galaxies, corrections for its influence must be made.
The idea of a non-empty interstellar space crystallized by the early 20th century. In 1904, J. Hartmann discovered absorption lines of ionized calcium that did not shift with the spectrum of a binary star—evidence of gas. Later, interstellar dust was suspected from the reddening and dimming effects on light from distant objects. Radio astronomy after World War II, especially the discovery of the 21 cm hydrogen line (1951), revolutionized the field: it became possible to map the spiral arms of the Galaxy. Space telescopes (IR infrared observatories IRAS, Spitzer, Herschel) made it possible to see cold dust. Today the ISM is studied across a multi-wavelength range: from radio to gamma rays.
The life of the ISM is a complex cycle. In molecular clouds, under self-gravity (often after a jolt from a supernova shock wave or a spiral density wave), cores collapse, giving birth to protostars. Ultraviolet radiation from massive stars ionizes the surrounding gas, creating HII regions. Stellar winds and supernova explosions enrich the medium with heavy elements and heat the gas. This feedback compresses neighboring clouds, triggering new episodes of star formation. Dust grains serve as catalysts for molecule formation (primarily H₂) and shield them from destructive UV radiation. A turbulent cascade transfers energy from large scales (supernova bubbles) to small, maintaining the kinetic state. Key physical processes: radiative cooling of rarefied plasma, thermal instability (leading to multiphase structure), and amplification of magnetic fields via a dynamo effect. Markers used for observations: rotational lines of CO (molecular gas), the 21 cm line (atomic hydrogen), recombination lines from HII regions, thermal emission from dust. Polarization of starlight by elongated dust grains aligned by the magnetic field allows inference of the field geometry. Laws: ideal gas (equation of state), radiative transfer (absorption and emission), magnetohydrodynamics (MHD), gravitational instability (Jeans criterion).
Analysis of the interstellar medium makes it possible to understand the life cycle of galaxies and the conditions for planet formation; without accounting for it, astronomical images from satellites like JWST would be misinterpreted due to absorption and scattering of light.
Dust in the interstellar medium is a veritable cosmic smog: microscopic grains (about 0.1 micron in size), which form in the cold atmospheres of old stars and gradually acquire icy mantles. Complex organic molecules have been discovered in dust grains—a sort of 'building blocks' for possible prebiotic chemistry.

























