object

retina

The light-sensitive layer of tissue at the back of the eye that converts light into neural signals.
21 related articles

Description

The retina is a thin layer of neural tissue at the back of the eye that converts incoming light into electrical signals, which are then transmitted to the brain via the optic nerve. It is a complex structure composed of photoreceptor cells (rods and cones), bipolar cells, and ganglion cells, among others. The retina is not just a passive sensor; it performs significant preprocessing of visual information, such as edge detection and contrast enhancement, before the signal reaches the brain.

History

The retina was first described in detail by the German physician and anatomist Heinrich Müller in the 19th century, who identified its various cell layers. The function of photoreceptors was later clarified by George Wald, who won the Nobel Prize in Physiology or Medicine in 1967 for his work on the visual pigments.

How it works

Light enters the eye and is focused onto the retina by the cornea and lens. Photoreceptor cells contain light-sensitive pigments, such as rhodopsin in rods, which undergo a conformational change when they absorb a photon. This triggers a biochemical cascade that alters the cell's membrane potential, ultimately reducing the release of the neurotransmitter glutamate. This change is picked up by bipolar cells and then relayed to ganglion cells, whose axons form the optic nerve. The retina's layered structure allows for lateral inhibition and other processing, enhancing the visual signal.

In practice

Understanding the retina is crucial for developing treatments for retinal diseases like macular degeneration and retinitis pigmentosa, as well as for designing retinal prostheses (bionic eyes) that can restore partial vision to the blind.

Fun fact

The retina is an extension of the brain, and it is the only part of the central nervous system that can be directly visualized from outside the body.

Concept graph →

Related articles · 21

q-bio.QM2026-09-112 minarXiv:2609.90039
SenSASP: a map of aging genes stitched together from four old ones
Four old maps were lying in different desk drawers. Each one marked genes linked to cellular aging, but the maps did not match: different names, different scales, different legends. A scientist hunting for a gene to test had to cross-check them by hand, at the risk of missing an important mark. SenSASP stitched those maps into one.
Optics2026-09-053 minarXiv:2609.06193
A Cell in a Dark Trap: Dividing Without Photodamage
In a dark room, you can hold a glowing sphere without touching it: walls of light push it away but do not burn it. That is roughly how the trap built in Rio de Janeiro for yeast cells works. A conventional optical tweezer, that is, a focused laser beam, acts like tweezers made of light, but the light itself pierces the cell from side to side.
A Neural Network That Counts Light in Ice
Imagine an interpreter at a meeting where everyone speaks a language they don't know. At first, they have to listen to every word, write it down verbatim, and then check against the original. That's how simulations for the IceCube neutrino telescope work: they track every photon born in the Antarctic ice, traveling hundreds of meters to hit a sensor.
Wood remembers when it was liquid
A slice of eucalyptus a tenth of a millimeter thick is placed under a polarized light microscope, and the wood suddenly blooms: blue, yellow, and pink bands twist into spirals, forming rings and swirls. This is not paint but the play of light: the cellulose fibers that make up cell walls transmit light differently depending on their orientation.
How the Visual Cortex Conducts the Thalamus
The brain is like an orchestra, with the cortex as the conductor and the thalamus as the first violin. The thalamus relays signals from the eyes to the visual cortex. But the cortex can also send commands back, tuning the thalamus for the task at hand. This was once a hypothesis, but now it's been tested in humans.
Optics2026-08-092 minarXiv:2608.08899express
Light Switches Crystal Without Heating
A stack of playing cards lies still. You can slide the top card with your finger: that's crude intervention. Or you can blow so that the whole stack momentarily changes shape, but the cards don't scatter. That's roughly how light, in a new experiment, rearranges a crystal of tin selenide (SnSe). Usually, to change the structure of a solid, you heat it or pass a current through it.
Chemical Physics2026-08-072 minarXiv:2608.07390express
Plant Quenches Its Internal Light in 60 Picoseconds
The lifetime of the entangled triplet pair in the protein is about 60 picoseconds, which is eight times longer than in solution. Sunlight is like a continuous stream of balls flying at a wall.
Signal Processing2026-08-021 minarXiv:2608.01239express
A Chip That Listens to Cells Building a Barrier
Blood vessel cells were seeded onto a transparent film just 700 nanometers thick — a hundred times thinner than a human hair. Flat electrodes are hidden beneath the film. They send a weak alternating current and listen as the resistance changes.
Medical Physics2026-07-281 minarXiv:2607.25749express
How MRI Peers Inside Nerve Fibers
Water inside nerve fibers doesn't move like it does in a glass: it constantly bumps into the walls of axons (the long projections of nerve cells). If you make the pause between MRI radio pulses very short, water doesn't have time to travel far, and its movement reflects the tightness of the surrounding space.
Memory Without Thoughts: How the Brain Remembers After Silence
After a stone is thrown, the circles on water vanish, but the liquid retains microscopic oscillations. The slightest gust, and ripples appear again. Neural networks behave similarly. When electrical signals quiet down, the memory of them remains in the contact points — synapses.
q-bio.QM2026-07-151 minarXiv:2607.14163express
Genes as a Dish: A Fresh Look at Cells
Data on gene activity usually looks like a long string of numbers, like a rainbow stripe (spectrum) with no visible connections. In the scVision model, these numbers are turned into a meaningful picture — not a list of ingredients, but a photo of a finished dish.
Signal Processing2026-07-141 minarXiv:2607.12518express
Cellular Echoes: How Your Phone Navigates Without GPS
A city signal bounces between walls like a ball, and your phone catches dozens of its 'reflections'—echoes. Each microsecond of delay adds 300 meters to the path. The signal's speed is constant, like that of light (speed of light).
Signal Processing2026-07-052 minarXiv:2607.04211express
Light Coils: MRI over Fiber Optics
Dozens of copper coils in an MRI scanner pick up the faint response from tissues, like microphones trying to catch a whisper in a noisy hall. Each microphone drags a thick bundle of wires behind it. The wires press on each other, create electrical interference, heat up, and add risk for the patient.
Applied Physics2026-05-302 minarXiv:2606.00818express
Silicon Retina: A Neuron Learns to See Like an Eye
A smartphone camera captures everything indiscriminately, but the eye immediately picks out what matters. The retina doesn't just pass the image to the brain: it highlights contours on the spot, suppresses noise, and adjusts to brightness.
Neurons Speak Plain Language
An artist paints a picture, glancing at the audience in the hall. If the viewer smiles, the artist adds more red and rounded lines to the canvas; if the viewer frowns, the artist removes blue and sharpens the angles.
Flexible Threads Turn Clothing into Radiation Detectors
Inside an ultra-thin polymer thread are microscopic crystals — scintillators. When an invisible radioactive particle hits, they flash for a moment, like fireflies. A sensitive sensor catches each flash, turning the thread into a flexible detector.
Optics2026-04-041 minarXiv:2604.03830express
Liquid Crystals Teach Light to Change the Rules
An ordinary lens always refracts light the same way. Its properties are frozen in glass forever. But now there's a surface that changes the game on the fly. Scientists made an ultrathin film with resonant elements and infused it with liquid crystals — the same stuff used in phone screens.
A Single-Celled Lens: How an Alga Confuses Light and Shadow
The tiny green alga Chlamydomonas spends its life rowing with two flagella toward light, like a swimmer heading for shore. It senses light with a photoreceptor protein, and behind it lies a red spot — the 'eyespot'—which casts a shadow and helps the cell figure out where the light is coming from.
Optics2026-01-252 minarXiv:2601.17694express
Light That Corrects Itself
A photo taken through frosted glass always comes out blurry. As light passes through a sample, it scatters, and the camera sees only a smudge instead of a sharp image. Scientists have long known how to recover an image from such a smudge, but old methods are finicky: they either get stuck on a wrong solution or require too many exposures, bombarding the fragile sample.
Biological Physics2025-10-111 minarXiv:2510.13840express
How Birds See Earth's Magnetic Field
Birds migrate using the magnetic field. In their eyes, there's a protein called cryptochrome. It captures sunlight, especially blue light, and triggers a reaction. Absorption of light leads to the formation of a particle pair that is acutely sensitive to magnetic fields.
Dense Connections vs. Residual Paths: How DenseNet-121 Outperforms ResNet-50 in Brain Cancer Detection
A brain tissue slice is just 5 microns thick, twenty times thinner than a human hair. On such a slice, a pathologist looks for signs of a tumor: altered nuclear shapes, cell crowding, abnormal blood vessels. It is painstaking work, and two specialists can disagree on the same image.