concept

hydrogen bond

A chemical bond involving hydrogen, whose connectivity affects proton jump likelihood in conductors.
22 related articles

Description

A hydrogen bond is a weak chemical bond between a hydrogen atom covalently attached to an electronegative atom (like oxygen or nitrogen) and another electronegative atom. It's not a true covalent bond but an electrostatic attraction that is crucial for the structure and properties of water, DNA, and proteins. The connectivity of these bonds determines how easily protons can jump between molecules, which is key for acid-base reactions and proton conduction in biological and materials systems.

History

The concept of the hydrogen bond was introduced by Wendell Latimer and Worth Rodebush in 1920, building on earlier work by Gilbert Lewis and others on chemical bonding.

How it works

The hydrogen atom in a polar bond (e.g., O-H) has a partial positive charge, while the electronegative atom (e.g., oxygen) has a partial negative charge. This creates an electrostatic attraction between the hydrogen and a nearby electronegative atom. The bond is directional and relatively weak (about 5-10% of a covalent bond), but collectively, hydrogen bonds can be very strong. In water, they form a dynamic network that constantly breaks and reforms, allowing protons to 'hop' along the network via the Grotthuss mechanism.

In practice

Hydrogen bonds are essential in drug design, as they determine how drugs bind to proteins. They are also exploited in materials science for creating self-healing polymers and in water purification technologies.

Fun fact

Hydrogen bonds are so sensitive to their environment that they can be used as 'fingerprints' to identify different drug molecules in spectroscopy.

Concept graph →

Related articles · 22

Superconductivity2026-08-162 minarXiv:2608.15745express
Superconductivity at pressures accessible to laboratories
An ordinary wire heats up when current flows through it — some energy is wasted. A superconductor lacks this flaw: electricity flows through it without loss, like water through a perfectly smooth pipe. The trouble is that most superconductors require either very low temperatures or colossal pressures, like those found in the depths of planets.
Biological Physics2026-08-092 minarXiv:2608.08571express
Why biological recognition doesn't snap but smoothly switches
When an antibody meets a virus, it doesn't latch on with a single death grip. Rather, it's like two bunches of grapes tumbling in water, catching each other with dozens of short tendrils. Each tendril is weak on its own, easily torn by the thermal jitter of water molecules, but together they hold tight.
Quantum Physics2026-08-072 minarXiv:2608.07257express
How Gravitational Waves Whisper to Matter
A stone drops into a pond, and ripples spread across the water. In the same way, massive bodies generate gravitational waves, except it's space itself that ripples. So far, these waves have been caught by giant detectors that barely flinch as a wave passes through. But what happens on the microscopic scale, inside a tiny piece of matter?
HEP Phenomenology2026-07-191 minarXiv:2607.17440express
A Trace of a New Force in Electron Waves
In a quiet room, you can hear the faintest whisper. Likewise, in the hydrogen atom, the lightest of all, an uninvited guest is easier to spot. That guest could be the Z' boson, a mediator particle of a new force predicted by many unification theories. The Standard Model already has its own mediator — the Z boson.
Chemical Physics2026-07-072 minarXiv:2607.06780express
Water dances: the hidden rhythm of hydrogen bonds
Water is not just a wet substance. On a picosecond scale, it resembles a dance floor where molecules continuously break and form bonds with each other. Usually, this dance is described by one main movement — collective relaxation, as if the whole crowd simultaneously slows down after the music stops.
HEP Phenomenology2026-06-152 minarXiv:2606.17133express
Pair Tango Inside the Proton
At accelerators, by smashing heavy nuclei, physicists briefly create a quark-gluon plasma — a state of matter where quarks and gluons are not confined inside particles but are free. For a long time, it was imagined as a gas, but experiments showed it's an almost perfect liquid.
How Hydrogen Breaks Steel in a New Way
A steel cylinder that has held hydrogen for a long time sometimes breaks not along the usual grain boundaries but right through the crystal grains, leaving a strange pattern, as if the crack chose the wrong road. For a long time, people looked at this and wondered: why?
Biological Physics2026-05-242 minarXiv:2605.24987express
How a cell catches broken DNA ends
A torn telephone wire is a nuisance, but a torn DNA is a catastrophe. A double-strand break, when both strands of the helix snap at the same spot, threatens the cell with death or transformation into cancer. Fortunately, the cell has its own 'glue': special proteins that gather into a droplet right at the accident site.
Chemical Physics2026-05-072 minarXiv:2605.06926express
A Positron in the Ring: How Atoms Attract an Antiparticle
A pinch of salt falls into water, and sodium and chlorine ions scatter, surrounded by water molecules. Now, instead of an ion, a positron (an antiparticle, the electron's twin but with a plus instead of a minus) joins the molecular crowd.
Strongly Correlated2026-05-052 minarXiv:2605.03526express
How Crystal Shape Changes the Color of Electrons
If you change not the composition but only the arrangement of atoms, you can make the same material conduct electricity or absorb light differently. That's exactly what the authors did with nickel and cobalt oxides. In one case, atoms are stacked like balls in a cubic box: each metal atom is surrounded by six oxygen atoms (rock salt structure).
Materials2026-05-011 minarXiv:2605.01045express
How Water Turns into Alkali and Back
In a crystal of water and caustic cesium, oxygen and cesium atoms sit in place like beads in a rigid lattice. Hydrogen atoms behave differently: they are like passengers constantly changing seats. In this layered material, each oxygen is linked to three neighbors via hydrogen bridges, forming a honeycomb-like pattern.
Machine Learning2026-04-251 minarXiv:2604.23115express
Hydrogen Bonds as Drug Fingerprints
When a key slides into a lock, it's not just the shape of the teeth that matters, but also how they press against the pins. In the world of drugs, hydrogen bonds play the role of these 'pressers'—weak but numerous bridges between the drug molecule and the target protein. They decide whether the drug holds on or slips off.
Galaxies2026-04-232 minarXiv:2604.21892express
How Invisible Hydrogen Is Rewriting the Chemistry of Space
A ball rolls up a hill, but it doesn't have enough energy, so it rolls back down. That's classical mechanics for you. But in the quantum world, a tiny particle can sometimes pass right through the hill, as if the barrier weren't there. This trick, tunneling, is business as usual for a light atom like hydrogen.
Chemical Physics2026-04-031 minarXiv:2604.03464express
How Water Dances with Carbon Rings
A water molecule, finding itself near a carbon ring, starts to vibrate, and immediately falls under the sway of an invisible conductor. The ring's electron cloud, like a maestro, dampens some vibrations while amplifying others.
Classical Physics2026-03-131 minarXiv:2603.13448express
The Invisible Ocean That Holds the Atom
According to ordinary mechanics, an electron in an atom should spiral into the nucleus and crash into it, like a surfer losing speed and falling off the board. But atoms live for billions of years. Because space isn’t empty. Even in absolute vacuum, an invisible electromagnetic sea ripples — the zero-point field. Its waves continuously nudge the electron.
Superconductivity2026-02-142 minarXiv:2602.13584express
A Kitchen Recipe for Superconductivity
An ordinary wire heats up when current flows through it. A superconductor doesn't. But almost all known superconductors require either very low temperatures or enormous pressures, like those deep inside planets. Scientists have long searched for a material that avoids these extremes.
Why Magnetic Fluid Forms Threads
In a jar of oily liquid float millions of tiny magnetic grains: each about the size of a bacterium. Switch on a magnet, and the grains, like obedient little soldiers, line up into long threads. But why do they form threads rather than clumps? It turns out it's not just about magnetism.
HEP Phenomenology2026-02-021 minarXiv:2602.02694express
A Hydrogen Trap for Dark Matter
Dark matter is invisible, but you can catch it on the rebound. Hydrogen embedded in a carbon film acts like a billiard ball: when a dark matter particle hits it, the proton flies out. That ejection is the signal you're looking for.
Materials2026-01-211 minarXiv:2601.14756express
A Lone Rhodium Atom Snaps Up Hydrogen Like a Trap
Chemistry has two worlds: in one, the catalyst is a solid particle and the reaction happens on its surface; in the other, it's a dissolved molecule where everything occurs around a single metal center. These worlds rarely meet. But in a new study, they collide. The researchers took iron oxide, a black powder used in magnetic tapes, and scattered single rhodium atoms across its surface.
How Bacteria Stick to Surfaces
A drop of oil in water behaves like a tiny ball: it seeks the spot with the least energy. If a wall is nearby, the drop often sticks to it, just as a raindrop spreads on glass. In a mixture of two immiscible liquids, such as polyethylene glycol and dextran, tiny droplets of one liquid form inside the other.
q-bio.BM2026-01-092 minarXiv:2601.14273express
Oxygen from Water: How Plants Build It Brick by Brick
In every leaf, in the light, a factory works that splits water into oxygen and hydrogen. The oxygen goes into the air we breathe, and the plant uses the hydrogen for food. The heart of this factory is a protein complex with four manganese atoms and one calcium atom.
Quantum Physics2025-12-011 minarXiv:2512.02156express
Hidden Wormholes in the Hydrogen Atom
Two water droplets tremble in sync — because they're connected by a straw. So it is with entangled particles: their unity may be held together by a microscopic wormhole.