
A bacterium is a microscopic single-celled organism that can adhere to surfaces and form magnetic chains.Bacteria are prokaryotic (lacking a nucleus) single-celled organisms of microscopic size (0.5–5 μm). Their circular DNA is concentrated in the nucleoid. The cell wall made of peptidoglycan gives shape (cocci, bacilli, spirilla) and protects against osmotic shock. They feed in various ways: photosynthesis (cyanobacteria), fermentation, respiration with or without oxygen. Plasmids – small circular DNA – often carry antibiotic resistance genes and are transferred between bacteria.
In 1665, Robert Hooke described the cellular structure of cork and later drew microorganisms, but the true discoverer of bacteria is considered to be Antonie van Leeuwenhoek (1676), who created lenses with 300x magnification. Louis Pasteur in the 1860s disproved the theory of spontaneous generation and proved that bacteria cause fermentation. Robert Koch (1876–1882) identified the causative agents of anthrax, tuberculosis, and cholera, and formulated Koch's postulates. Alexander Fleming in 1928 discovered penicillin. Carl Woese in 1977, based on analysis of 16S rRNA, separated archaea, dividing prokaryotes into two domains.
The exponential growth phase is described by the formula N(t)=N₀·2^(t/g). In stationary phase, stress-resistance genes are turned on. Chemotaxis: a network of signaling proteins (CheA, CheY) controls the direction of flagellar rotation, enabling bacteria to swim along gradients of attractants. Quorum sensing: using autoinducers (e.g., AHL in gram-negatives), bacteria assess their density and coordinate behavior – synchronously switching on bioluminescence or virulence genes. Transcription of operons (e.g., lac operon) is regulated by repressors and inducers.
Bacteria ferment yogurt and kefir, produce insulin for diabetics, and help extract useful minerals from low-grade ores.
The total mass of bacteria on Earth exceeds the mass of all plants and animals combined.





















