Geometric property of a molecule that is not superimposable on its mirror image.Chirality is a geometric property where an object cannot be superimposed on its mirror image, like left and right hands. In molecules, chirality means two versions exist that are mirror images but not identical — called enantiomers. These can have vastly different chemical and biological effects, which is why chirality is central to pharmacology, biochemistry, and fundamental physics.
Louis Pasteur first discovered molecular chirality in 1848 when he manually separated left- and right-handed crystals of tartaric acid and observed their opposite effects on polarized light.
Chirality arises when a molecule has an asymmetric center, typically a carbon atom bonded to four different groups. The two arrangements are mirror images, like left and right gloves. They have identical physical properties (mass, boiling point) but interact differently with other chiral objects, such as enzymes or polarized light. In physics, chirality also refers to the handedness of particles, related to their spin and momentum.
Chirality is exploited in drug design (one enantiomer may be therapeutic, the other toxic), in chiral catalysis for producing specific enantiomers, and in optical technologies using circularly polarized light.
The weak nuclear force violates chirality symmetry — it only interacts with left-handed particles and right-handed antiparticles, which is why the universe is made of matter rather than antimatter.











