The ability of a sensor to detect small changes in the measured quantity, often expressed as a minimum detectable signal.Sensitivity in physics refers to the smallest change in a measured quantity that a sensor or instrument can reliably detect. It is crucial for precision measurements in fields like quantum sensing, where detecting tiny magnetic fields, forces, or frequencies can reveal new physics or enable advanced technologies. High sensitivity often involves minimizing noise and amplifying the signal from the phenomenon of interest.
The concept of sensitivity has evolved with measurement science, from early galvanometers in the 19th century to modern quantum sensors. Specific milestones include the development of SQUIDs (superconducting quantum interference devices) in the 1960s, which achieved unprecedented magnetic field sensitivity.
Sensitivity is achieved by designing sensors that respond strongly to small perturbations, often using resonant effects, quantum coherence, or amplification. For example, atomic magnetometers use the precession of spins in a magnetic field, where even minute field changes alter the precession frequency, which can be measured with high precision. Noise reduction techniques, such as cooling or shielding, further enhance sensitivity.
High-sensitivity sensors are used in medical imaging (MEG), geological surveys, navigation (quantum gyroscopes), and fundamental physics experiments like gravitational wave detectors.
Some quantum sensors can detect magnetic fields a billion times weaker than Earth's magnetic field, enabling them to pick up signals from a single neuron firing in the brain.
| LOD | variable | limit of detection — limit of detection mole per cubic metre |
| k | variable | confidence factor (typically 3) — confidence factor |
| σ_noise | variable | standard deviation of the blank signal — noise standard deviation |
| sensitivity | variable | slope of calibration curve (signal per concentration) — sensitivity cubic metre per mole |













