A pair of molecules with unpaired electrons whose spin dynamics can be magnetic-field sensitive.A radical pair is a pair of molecules or molecular fragments, each carrying an unpaired electron, that are created together and whose spins are quantum-mechanically correlated. The pair's spin state can interconvert between singlet and triplet configurations, and this interconversion is sensitive to external magnetic fields. This makes radical pairs a key mechanism for biological magnetoreception, as in birds' ability to sense Earth's magnetic field, and also for certain chemical reactions in the lab.
The radical pair mechanism was proposed by Adrian and McLachlan in 1962 to explain magnetic field effects on chemical reactions, and later applied to avian magnetoreception by Klaus Schulten in 1978.
When a molecule absorbs light, it can split into two radicals with correlated electron spins. The spins precess in the local magnetic environment, and their relative orientation oscillates between singlet (opposite spins) and triplet (parallel spins). The rate of this oscillation depends on the strength and orientation of an external magnetic field. The two spin states lead to different chemical products, so the magnetic field effectively controls the reaction's outcome. In birds, this happens in cryptochrome proteins in the retina, where the radical pair's spin dynamics are thought to encode directional information.
Radical pair mechanisms are used in chemical magnetometers, in understanding magnetic field effects on biological tissues, and in designing spin-based sensors.
Some migratory birds can detect magnetic field changes as small as a few dozen nanoteslas, which is about 1/1000th of Earth's field strength.
















